[tabs]
[tab title=2005]
Therapeutic efficacy of sulfadoxine-pyrimethamine and amodiaquine among children with uncomplicated Plasmodium falciparum malaria in Zanzibar, Tanzania.Lemnge MM, Ali AS, Malecela EK, Sambu E, Abdulla R, Juma MS, Fakih K, Abdulla KH, Njau RJ.Am J Trop Med Hyg. 2005 Oct;73(4):681-5. [Read more>>]
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[tab title=2004]
1. Therapeutic efficacy of sulfadoxine-pyrimethamine and prevalence of resistance markers in Tanzania prior to revision of malaria treatment policy: Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase mutations in monitoring in vivo resistance. Mugittu K, Ndejembi M, Malisa A, Lemnge M, Premji Z, Mwita A, Nkya W, Kataraihya J, Abdulla S, Beck HP, Mshinda H.Am J Trop Med Hyg. 2004 Dec;71(6):696-702. [Read more>>]
2. Two mutations in dihydrofolate reductase combined with one in the dihydropteroate synthase gene predict sulphadoxine-pyrimethamine parasitological failure in Ugandan children with uncomplicated falciparum malaria. Talisuna AO, Nalunkuma-Kazibwe A, Langi P, Mutabingwa TK, Watkins WW, Van Marck E, Egwang TG, D'Alessandro U.Infect Genet Evol. 2004 Dec;4(4):321-7. [Read more>>]
3. Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites. Bates SJ, Winstanley PA, Watkins WM, Alloueche A, Bwika J, Happi TC, Kremsner PG, Kublin JG, Premji Z, Sibley CH.J Infect Dis. 2004 Nov 15;190(10):1783-92. [Read more>>]
4. Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial. Alloueche A, Bailey W, Barton S, Bwika J, Chimpeni P, Falade CO, Fehintola FA, Horton J, Jaffar S, Kanyok T, Kremsner PG, Kublin JG, Lang T, Missinou MA, Mkandala C, Oduola AM, Premji Z, Robertson L, Sowunmi A, Ward SA, Winstanley PA.Lancet. 2004 Jun 5;363(9424):1843-8. [Read more>>]
5. Efficacy of sulphadoxine-pyrimethamine alone or combined with amodiaquine or chloroquine for the treatment of uncomplicated falciparum malaria in Ugandan children.Talisuna AO, Nalunkuma-Kazibwe A, Bakyaita N, Langi P, Mutabingwa TK, Watkins WW, Van Marck E, D'Alessandro U, Egwang TG.Trop Med Int Health. 2004 Feb;9(2):222-9. [Read more>>]
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[tab title=2003]
1. Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa. Ochong E, Nzila A, Kimani S, Kokwaro G, Mutabingwa T, Watkins W, Marsh K.Malar J. 2003 Dec 15;2(1):46. [Read more>>]
2. Prediction of Plasmodium falciparum resistance to sulfadoxine/pyrimethamine in vivo by mutations in the dihydrofolate reductase and dihydropteroate synthetase genes: a comparative study between sites of differing endemicity. Alifrangis M, Enosse S, Khalil IF, Tarimo DS, Lemnge MM, Thompson R, Bygbjerg IC, Rønn AM.Am J Trop Med Hyg. 2003 Dec;69(6):601-6. [Read more>>]
3. Increasing prevalence of wildtypes in the dihydrofolate reductase gene of Plasmodium falciparum in an area with high levels of sulfadoxine/pyrimethamine resistance after introduction of treated bed nets. Alifrangis M, Lemnge MM, Rønn AM, Segeja MD, Magesa SM, Khalil IF, Bygbjerg IC.Am J Trop Med Hyg. 2003 Sep;69(3):238-43. Erratum in: Am J Trop Med Hyg. 2003 Nov;69(5):564. [Read more>>]
4. Intensity of transmission and spread of gene mutations linked to chloroquine and sulphadoxine-pyrimethamine resistance in falciparum malaria. Talisuna AO, Langi P, Mutabingwa TK, Van Marck E, Speybroeck N, Egwang TG, Watkins WW, Hastings IM, D'Alessandro U.Int J Parasitol. 2003 Sep 15;33(10):1051-8. [Read more>>]
5. Population-based validation of dihydrofolate reductase gene mutations for the prediction of sulfadoxine-pyrimethamine resistance in Uganda. Talisuna AO, Langi P, Mutabingwa TK, Watkins W, Van Marck E, Egwang TG, D'Alessandro U.Trans R Soc Trop Med Hyg. 2003 May-Jun;97(3):338-42. [Read more>>]
6. Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: a randomised placebo-controlled trial. Massaga JJ, Kitua AY, Lemnge MM, Akida JA, Malle LN, Rønn AM, Theander TG, Bygbjerg IC.Lancet. 2003 May 31;361(9372):1853-60. [Read more>>]
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[tab title=2002]
1. Highly pyrimethamine-resistant alleles of dihydrofolate reductase in isolates of Plasmodium falciparum from Tanzania. Hastings MD, Bates SJ, Blackstone EA, Monks SM, Mutabingwa TK, Sibley CH.Trans R Soc Trop Med Hyg. 2002 Nov-Dec;96(6):674-6. [Read more>>]
2. Role of the pfcrt codon 76 mutation as a molecular marker for population-based surveillance of chloroquine (CQ)-resistant Plasmodium falciparum malaria in Ugandan sentinel sites with high CQ resistance. Talisuna AO, Kyosiimire-Lugemwa J, Langi P, Mutabingwa TK, Watkins W, Van Marck E, Egwang T, D'Alessandro U.Trans R Soc Trop Med Hyg. 2002 Sep-Oct;96(5):551-6. [Read more>>]
3. A point mutation in codon 76 of pfcrt of P. falciparum is positively selected for by Chloroquine treatment in Tanzania. Schneider AG, Premji Z, Felger I, Smith T, Abdulla S, Beck HP, Mshinda H.Infect Genet Evol. 2002 May;1(3):183-9. [Read more>>]
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